THE CONTRIBUTION OF THE 20S PROTEASOME TO PROTEOSTASIS

The Contribution of the 20S Proteasome to Proteostasis

The last decade has seen accumulating evidence of various proteins being degraded by the core 20S proteasome, without its regulatory particle(s).Here, we will describe recent advances in our knowledge of the functional aspects of the 20S proteasome, exploring several different systems and processes.These include neuronal communication, post-transla

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Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions

It is believed that human Influenza HA glycoprotein attaches to alpha2-6 linked sialic acids (SA) on cells, while avian viruses bind to alpha2-3 linked sialic acids, therewith contributing to host tropism.Here, Liu et al.show jonquille comestible that mixing low-affinity alpha2-3 SA with low amounts of high-affinity alpha2-6 SA increases binding an

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OPTIMIZING THE GROWTH AND DEVELOPMENT OF TODDLERS THROUGH EMPOWERING CADRES AND MOTHERS OF TODDLERS WITH ASIKIA ACTIVITIES

The toddler period is a vulnerable time, especially with regard to growth, as it can affect the development of children in the future.Therefore, it is necessary to intervene to increase the interaction of health professionals with parents to have a positive impact on child development.The Maternal and Child Health Information Sharing Agenda (ASIKIA

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